Search results for "Atherosclerotic plaques"
showing 3 items of 3 documents
Plasma phospholipid transfer protein (PLTP) modulates adaptive immune functions through alternation of T helper cell polarization
2016
International audience; Objective: Plasma phospholipid transfer protein (PLTP) is a key determinant of lipoprotein metabolism, and both animal and human studies converge to indicate that PLTP promotes atherogenesis and its thromboembolic complications. Moreover, it has recently been reported that PLTP modulates inflammation and immune responses. Although earlier studies from our group demonstrated that PLTP can modify macrophage activation, the implication of PLTP in the modulation of T-cell-mediated immune responses has never been investigated and was therefore addressed in the present study. Approach and results: In the present study, we demonstrated that PLTP deficiency in mice has a pro…
Efficacy of Magnetic Resonance Imaging in assessing the Prognosis of Atherosclerotic plaques in patients under Statin Therapy: A Systematic Review of…
2021
The current study aims to conduct a systematic review on the efficacy of Magnetic Resonance Imaging (MRI) in assessing the Prognosis of Atherosclerotic plaques in patients under Statin Therapy. For this purpose, the existing studies focusing on these criteria and the clinical trials and studies have been focused upon. The time frame set for the evaluation of the present literature and findings has been set at the previous decade i.e. the studies of the previous 10 years have been searches through authentic databases and the data related to the current topic has been extracted through efficient sources and reviewers. All the details about MRI efficacy in the assessment of prognosis of Athero…
Sténoses carotidiennes athéromateuses : causes fondamentales et conséquences cliniques
2014
The treatment of high-grade carotid stenosis is surgery combined with best medical treatment. We established since 2003, a prospective database including all patients hospitalized in our vascular surgery department for management of carotid stenosis. Since 2012, the clinical database was completed for the establishment of a biological database. We present here the method of setting up such a database, and the results of four original studies on the theme of "high-risk patient" for carotid surgery: the influence of renal function, of the delay between symptoms and surgery and of the contralateral carotid artery on outcome and the proposal of a prognostic score of intolerance to carotid clamp…